The 14-game unbeaten run of Nottingham Forest was brought comprehensively to a halt by a Burnley side sitting pretty in one of the two automatic promotion spots in the Championship.
A brace from Sam Vokes after Scott Arfield had put the Clarets into the lead had the Reds floundering and they could only manage a consolation strike in the 80th minute from Djamel Abdoun from the penalty spot at the second attempt after his first effort was saved.
Forest arrived at Depdale not having lost a league game since November.
But Arfield had already had one shot cleared off the line before he opened the scoring in the 12th minute.
Hotshot marksman Vokes then took over with goals in the 25th minute with a header and the 35th when his shot deflected past Karl Darlow.
It effectively killed the game as a contest before the half-time whistle.
It means Forest must turn their attentions to securing a play-off spot as they are now eight point behind Burnley and 16 behind leaders and East Midlands rivals Leicester City, against whom they drew 2-2 at the City Gorund in midweek.